Boehner Proposes Tax-Rate Rise (WSJ)

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Researchers Find More Than 200 Genes Linked to Crohn's Disease

British scientists have identified more than 200 gene locations associated with Crohn's disease, an incurable digestive disorder. Their research utilized the entire human genome, the complete set of human genetic information stored in DNA.

The total is larger than the number of genes located for any other disease, according to ScienceDaily. For example, there are 66 known locations for type 2 diabetes.

The researchers, from University College London (UCL), believe that their findings will eventually lead to more personalized Crohn's treatment. The disorder is one of the two principal types of inflammatory bowel disease (IBD). The other is ulcerative colitis. The Crohn's & Colitis Foundation of America states that Crohn's affects up to 700,000 Americans. It typically strikes between 15 and 35, but can occur at any age.

The exact cause of the disorder has eluded researchers for decades. Most experts believe that several factors play important roles in the development of the disease. Those cited most often are genetics, environmental factors, and an abnormal immune reaction to benign substances like bacteria in the intestines. Crohn's is a chronic illness that can involve any part of the digestive tract from mouth to anus, according to PubMed Health.

Scientists have believed for years that understanding the genetic component of such a complex disease is critical to explaining symptoms and developing better methods of treatment. However, they have remained stymied over detailed genetic mapping for the disorder because of the large number of genes involved, complex interactions with the environment, and a wide range of symptoms.

The British team utilized data from a consortium with information on nearly 1,700 Crohn's patients. Data provided by the U.S. National Institute of Diabetes and Digestive and Kidney Diseases on 813 patients led to replication of results of the British study.

Results from the UCL study appeared in the American Journal of Human Genetics. One of the factors the team believes was responsible for their success was use of highly detailed maps of the human genome. Another was their ability to subdivide Crohn's patients by the way they presented with the disorder. The results also represent the first definite signs that certain patient sub-groups are predisposed to carry different risk genes.

Like most patients who have had this illness for decades, I often become impatient when I read about a discovery linked to the genetics of Crohn's disease. Since about 20 percent of patients have a close family member with IBD, years ago, I asked whether I should have my daughter tested.

The doctor and I agreed that it was pointless. Her symptoms were either due to Crohn's or not. Time would tell. From a patient's perspective, what is strikingly different about the identification of more than 200 genes is the hope that it will lead to more personalized treatment, not just more data on a library shelf.

Vonda J. Sines has published thousands of print and online health and medical articles. She specializes in diseases and other conditions that affect the quality of life.

Source: http://news.yahoo.com/researchers-more-200-genes-linked-crohns-disease-231000090.html

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Loan For Debt Consolidation In Australia Finance Your All Overdue ...

The recent problems in the financial world in the United States and Europe were mainly due to the lax diligence by many banks and bankers when sanctioning loans to individuals and companies. That rosy bubble suddenly burst when the economy took a nosedive, and people and companies could not repay their loans when it became due, and in some cases could not even meet the interest payments.

Pacifying Your Creditors With Debt Consolidation
Here in Australia, the situation was not as bad as in the United States and Europe, but there were many cases of people defaulting on their loans and in some cases declaring bankruptcy. As a solution to this problem, debt management companies have risen to the occasion and have come up with different solutions to fix the problem. One of the tools in debt management has been the loan consolidation of debt which can help in reducing some of the accumulated debt. A loan for debt consolidation can be arranged by the debt manager, giving you a new beginning with assistance to manage your current debts. The advantage of this loan for debt consolidation is that it is designed to cover wide range of accumulated debts, including housing loans, student loans, credit card bills, personal loans, and medical bills, etc.

Peace Of Mind With A Consolidation Loan
A loan consolidation of debt is designed to consolidate all existing outstanding debts into one loan with a low interest rate that is typically arranged by your debt manager. A loan for debt consolidation gives you some relief from the incessant calls and threats of creditors and debt collection agencies regarding your outstanding loan repayments. One of the biggest benefits of a loan for debt consolidation is the peace of mind that the debtor and his family gets once the debt managers start their work. The biggest advantage for the debtor is that he will only have to think about repaying one consolidated loan which has been negotiated on his behalf by the debt manager.

Manage Your Debts Carefully With Help
Once the debt manager finalizes a loan provider, they will assess your financial situation before signing any repayment schedule. After that, there should not be any problem with creditors harassing you about repayment or any loan default process. A loan for debt consolidation can help you improve your credit history, which could affect you severely in the future if there was a loan default. A loan consolidation of debt negotiated by the debt manager comes in two types, secured or unsecured loans. After the initial assessment has been complete, and following the advice of the debt manager, you can go about choosing which of the two options is suitable for you.

About the Author:
If you have any debt problem. In this situation, you can easily found a good help about loan consolidation of debt. Credit Consolidation Loans gives you some breathing space from your worried creditors.

Source: http://www.articlesnatch.com/Article/Loan-For-Debt-Consolidation-In-Australia-----Finance-Your-All-Overdue-Debts/4320275

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Analyzing Keyword Profits | Internet Marketing for Small Business ...

Pay per click advertising is a highly successful way to promote
your online business and increase your sales. However, like all
other internet marketing tactics, pay per click advertising
isn?t for everyone. For this reason, you may be wondering
whether or not pay per click advertising can help you. To
determine whether or not you can benefit from pay per click
advertising, you need to examine the profitability of keywords,
namely the keywords that you would choose to be associated with
your ads.

If this is your first time participating in a pay per click
program, you may be wondering about keywords, namely what they
are and what they are used for. When further examining pay per
click advertising, you will see that all advertisements are
associated with keywords. Those keywords are matched up with
keywords from various different online websites; the websites
that choose to participate in a pay per click program. These
keywords will also determine the amount of money that you will
have to pay for advertising.

When it comes to choosing your keywords, there are a number of
important factors that should be taken into consideration. Those
factors include relation and popularity. You will want to choose
keywords that are related to your online business or the
products that you are looking to sell. For popularity, you want
to choose keywords that are popular or ones that are actively
being used in search engines. These two factors will help to
ensure that your ads will not only be seen, but that they will
be seen by the right people, your targeted market.

Once you have determined what keywords you would like to use,
you can then use a program that is often referred to as a
keyword worth tool. One of these programs can be found by
visiting http://uv.bidtool.overture.com/d/USm/search/tools/bidtool/.

By entering in the keywords or the keyword phrases of your choice,
you will be shown sample advertisements and how much they cost.
This tool will give you an accurate idea of how much you can
expect to pay for each keyword that you would like your
advertisements to be associated with.

As nice as it is to have an idea as to how much you would have
to pay for a particular keyword advertisement, you may also be
wondering if you can profit from that advertisement. To do
this, you will need to examine what you are trying to sell. If
you are trying to sell a particular product, you will want to
take the price of that product and subtract it from the
estimated keyword cost that you were given, when you used the
above mentioned tool or a similar one. If you are just
advertising your business in general, you will want to take your
average sale amounts and subtract them from the estimated cost
of your keywords.

When using the above mentioned formula to calculate the
profitability of a keyword advertisement, there are some
additional factors that should be taken into consideration. For
instance, the price of a keyword advertisement can change at any
given time. This means that the price you have to pay may
increase or decrease. It is also important to remember that not
all of your advertisement clicks result in a sale, but you will
still be charged for each click. To get a more accurate
estimate of profitability, it may be best to prepare for
non-clickers. In fact, you may want to assume that only five out
of ten clicks will result in a sale. This may help to give you a
more accurate estimate of the profits that you may see when
participating in a pay per click program.

Although it is best if you can profit from pay per click
advertising, you may still want to give it a try, even if you
feel that you cannot. With pay per click advertising, you are
able to limit the amount of money that you spend each day. Being
able to control the amount of money that you may lose is just
one of the many reasons why you should give pay per click
advertising a trial run.

Estimating the amount of money that you will have to pay
for advertisements, as well as your profits, is a great way to
determine whether or not pay per click advertising is for you.

Search Engine Optimization Services

Source: http://www.onlinemediamagic.com/blog/2004/analyzing-keyword-profits/

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